Mathematical Science Seminar: new methods for multi-locus genome-wide association studies and mrMLMv3.0 software package

Events

Speaker

Prof Yuanming Zhang, College of Plant Science and Technology, Huazhong Agricultural University

Prof Yuanming Zhang, Professor of Statistical Genomics, holds a titled Chutian Scholar professorship. He is one of the leading professors in heredity and statistical genomics. He is associated editors for several leading journals including Heredity, Scientific Reports, and Frontiers in Plant Science, BMC Genetics and Canadian Journal of Plant Science.


Language

Prof Zhang prefers to give the talk in Chinese for efficiency with English slides.


Abstract

Genome-wide association studies (GWAS) have been widely used in the genetic dissection of quantitative traits in human, animal and plant genetics, especially in combination with the output of genomic sequencing technologies. Although nonparametric methods in genome-wide association studies (GWAS) are robust in quantitative trait nucleotide (QTN) detection, the absence of polygenic background control in single-marker association in genome-wide scans results in a high false positive rate. In this seminar, Prof Zhang, will present their very recent results and software packages on multi-locus genome-wide association studies, which is featured publication by the leading Journal heredity by Nature Publication.