Chemistry Department Seminar: Nanoscale Engineering of Plasmonic Materials for Biosensing



Dr Fang Xie

(Department of Materials, Imperial College London, SW7 2AZ, UK)

Dr Fang Xie is a Senior Lecturer at Department of Materials, Imperial College London. She is also Deputy Director for MSc in Advanced Materials. She has expertise in functional nanomaterials including metal, semiconducting, and oxide nanomaterials synthesis, as well as the applications of the functional materials in energy and life sciences. Her current research interests include plasmonic nanostructures for efficient light harvesting for solar cells and solar fuels, as well as in ultrasensitive biosensing and Bioimaging applications. She has over 50 publications including five patents. She has also delivered a number of keynote and invited talks in the international conferences.


Early diagnosis plays an increasingly significant role in current clinical drive. Detection, identification, and quantification of low abundance biomarker proteins form a promising basis for early clinical diagnosis and offer a range of important medical benefits. Amplification of light from NIR fluorophores by coupling to metal nanostructures, i.e. Metal Induced Fluorescence Enhancement (MIFE), represents a promising strategy for dramatically improving the detection and quantification. The amplification of the fluorescence system is based on interaction of the excited fluorophores with the surface plasmon resonance in metallic nanostructures. The first part of the talk will focus on some recent developments of plasmonic metal nanostructures by both “top-down” and “bottom up” methods. I will then discuss the prepared plasmonic nanostructures in the applications of biosensing.