Yi Li is now Associate Professor in the Department of Chemistry at Xi'an Jiaotong-Liverpool University. He studied for his PhD with Professor Manfred Hesse at the University of Zurich, investigating the synthesis of polyamine alkaloids. He then held Postdoctoral Fellowships with Professor Tony Barrett at Imperial College, London, and Professor Karl Hale, at University College London and Queen's University, Belfast. In 2008, Yi Li joined Professor Gerry Pattenden at the University of Nottingham to study the biomimetic synthesis of complex polycyclic diterpenes found in corals. He was first appointed as Lecturer in the Department of Chemistry at Xi'an Jiaotong-Liverpool University in 2011 and promoted to the current position in 2015. Yi Li's research interests have been in the development of strategies for organic synthesis and total synthesis of biologically active natural products.
Ph.D. , Organic Chemistry; University of Zürich, Switzerland, - 2002
M.C. , Master of Chemistry; The University of New South Wales, Australia, - 1998
Lecturer, Department of Chemistry, Xi'an Jiaotong-Liverpool University, China - 2011 to Present
Research Fellow (with Prof. Gerry Pattenden, FRS), School of Chemistry, University of Nottingham - 2008 to 2011
Postdoctoral Research Fellow (with Prof. Karl Hale), University College London and Queen's University, Belfast - 2004 to 2008
Postdoctoral Research Fellow (with Prof. Tony Barrett, FRS), Department of Chemistry, Imperial College - 2002 to 2004
Organic Synthesis and Natural Products
Natural products have served as the invaluable sources for drug discovery and the inspiration of organic synthesis which remains the cornerstone of future developments in biosciences, materials science, medicine and molecular engineering for decades to come.
My research focuses on the synthetic studies of select natural products of biomedical significance and the development of synthetic methodology for the construction of complex, biologically intriguing molecules.
Li, Yi & Pattenden, G. 2011 'Novel Macrocyclic and Polycyclic Norcembranoid Diterpenes from Sinularia sp of Soft Coral. Structural Relationships and Biosynthesis Speculations', Nat. Prod. Rep., vol. 28, no. , p. 429-440
Li, Yi & Pattenden, G. 2011 'Exploration of a proposed biomimetic synthetic route to plumarellide. Development of a facile transannular Diels-Alder reaction from a macrocyclic enedione leading to a new 5,6,7-tricyclic ring system', Tetrahedron Lett, vol. 52, no. , p. 2088-2092
Li, Yi & Pattenden, G. 2011 'Photochemical isomerisation studies of rubifolide and bipinnatin J. Unravelling some of the biosynthesis interrelationships between macrocyclic and polycyclic cembranoids found in corals', Tetrahedron Lett, vol. 52, no. , p. 3315-3319
Li, Yi & Pattenden, G. 2011 'Perspectives on the structural and biosynthetic interrelationships between oxygenated furanocembranoids and their polycyclic congeners found in corals', Nat. Prod. Rep., vol. 28, no. , p. 1269-1310
Li, Yi & Pattenden, G. 2011 'Biomimetic syntheses of ineleganolide and sinulochmodin C from 5-episinuleptolide via sequences of Transannular Michael reactions', Tetrahedron, vol. , no. , p.
Yang, Z., Li, Y. & Pattenden, G. 2010 'Synthesis of E-deoxypukalide, and its biomimetic conversion into deoxypseudopterolide by photochemical ring contraction involving a 1,3-allylic shift', Tetrahedron, vol. 66, no. , p. 6546-6549
Li, Yi, Pattenden, G. & Rogers, J. 2010 'Synthesis of exo enol ether cyclic ketal isomers of substituted furanmethanol structures related to marine furanocembranoids', Tetrahedron Lett, vol. 51, no. , p. 1280-1283
Li, Yi, Nawrat, C. C., Pattenden, G. & Winne, J. M. 2009 'A Concise Total Synthesis of (±)Anthecularin', Org. Biomol. Chem., vol. 7, no. , p. 639-640
Li, Yi & Hale, K. J. 2007 'Asymmetric Total Synthesis of the Antitumour Sesquiterpenoid, (+)-Eremantholide A', Org. Lett., vol. 9, no. , p. 1267 – 1270
Li, Yi 2013, Principal Investigator, New methods for the Asymmetric Trifluoromethylation of Organic Molecules, 100000.0000, Jiangsu Science and Technology Programme