Xi'an Jiaotong-Liverpool University

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Dr. Cheng joined the Academy of Pharmacy at XJTLU as an assistant professor in Sep. 2021. She has broad experience in mass spectrometry and NMR-based comprehensive metabolomics and lipidomics studies. She has also been working on biomarker discovery and patient stratification via integrated study of multi-omics data, and investigating the regulatory mechanism of bioactive compounds on health and metabolic disease risk in intervention studies.

Contact me via email (ken.cheng@xjtlu.edu.cn) if you are interested in collaboration with us.

Research key words:
metabolomics, multi-omics, mass spectrometry, biomarker, bioactive compounds in natural products

Qualifications
- Bsc, Harbin Institute of Technology, Harbin, 2005-2009
- Master, Universite de Rennes and Agrocampus Ouest, Rennes, 2009-2012
- PhD, Swedish University of Agricultural Science, Uppsala, 2012-2017
Experience
- Assistant professor, Academy of Pharmacy, XJTLU, Suzhou, 2021-present
- Honorary Academic Staff, University of Liverpool, 2021-present
- Senior researcher, Shenzhen Digital Life Institute (iCarbonX), Shenzhen, 2018-2021
- Postdoc, Department of Food and Nutrition Science, Chalmers Institute of Technology, Goteborg (Sweden), 2017-2018
- French translator, I-TEK, Tremeur (France), 2012
Research interests
- Exploration of novel biomarkers and establishment of diagnostic and predictive models based on multiple omics data, especially metabolome, proteome and gut microbiota, and multi-dimensional data integration approaches.
- Regulatory mechanism investigation of bioactive compounds in metabolic diseases.
- Mass spectrometry-based analytical methods for comprehensive coverage of metabolome and lipidome.
Articles
- Cheng, K.#, Brunius, C., Landberg, R. (2020) An LC-QToF MS based method for untargeted metabolomics of human fecal samples. Metabolomics 16:46.
- Luo, S., ...... Cheng, K., et al. (2023). Flaconifractor plautii protects against elevated arterial stiffness. Circulation research 132:00-00.
- Cheng, K.*, Luan, E.*, Long, Q., et al. A reference feature table-based method for profiling LC-MS-based untargeted metabolomics. (submitted)
- Cheng, K.#, Marta, B., Ruyter, B., Pickova, J., Ehtesham, E., Du, L., Venegas, C., and Moazzami, A.A. (2018) Impact of reduced dietary levels of eicosapentaenoic acid and docosahexaenoic acid on the composition of skin membrane lipids in Atlantic salmon (Salmo salar L.). Journal of Agricultural and Food Chemistry 66(33), 8876-8884.
- Cheng, K.#, Müllner, E., Moazzami, A.A., Carlberg, H., Brännäs, E., and Pickova, J. (2017) Metabolomics approach to evaluate a Baltic Sea sourced diet for cultured Arctic char (Salvelinus alpinus L.). Journal of Agricultural and Food Chemistry 65, 5083-5090.
- Cheng, K., Ropers, M.-H., and Lopez, C. (2017) The miscibility of milk sphingomyelin and cholesterol is affected by temperature and surface pressure in mixed Langmuir monolayers. Food Chemistry 224, 114-123.
- Cheng, K.#, Wagner, L., Moazzami, A.A., Gómez-Requeni, P., Schiller Vestergren, A., Brännäs, E., Pickova, J., and Trattner, S. (2016). Decontaminated fishmeal and fish oil from the Baltic Sea are promising feed sources for Arctic char (Salvelinus alpinus)–Studies of flesh lipid quality and metabolic profile. European Journal of Lipid Science and Technology 118(6), 862-873.
- Cheng, K.#, Wagner, L., Pickova, J., and Moazzami, A.A. (2016). NMR-based metabolomics reveals compartmental metabolic heterogeneity in liver of Arctic char (Salvelinus alpinus). Canadian Journal of Zoology 94(9), 665-669.
- Wang, M., …… Cheng, K., et al. An integrative multi-omic view of molecular dynamics in human subjects undergoing fasting-refeeding course. (submitted)
- Fredriksson, R., …… Cheng, K., et al. (2019) The polyamine transporter Slc18b1(VPAT) is important for both short and long-time memory and for regulation of polyamine content in the brain. PLoS Genetics 15(21), e1008455.
- Lopez, C., Cheng, K., Perez, J. (2018). Thermotropic phase behavior of milk sphingomyelin and role of cholesterol in the formation of the liquid ordered phase examined using SR-XRD and DSC. Chemistry and Physics of Lipids 215, 46-55.
- Carlberg, H., Cheng, K., Lundh, T., and Brännäs E. (2015). Using self-selection to evaluate the acceptance of a new diet formulation by farmed fish. Applied animal behaviour Science 171, 226- 232.
- Carlberg, H., Lundh, T., Cheng, K., Pickova, J., Langton, M., Gutiérrez, J.L.V., Kiessling, A., and Brännäs, E. (2018). In search for protein sources: evaluating an alternative to the traditional fish feed for Arctic charr (Salvelinus alpinus L.). Aquaculture 486, 253-260.
Courses taught
- APH001, Explore Pharmaceutical Sciences (module leader)
- APH002, Introduction to Basic Science of Medicine (module leader)
- APH004, Brief History of Drug Discovery (module leader)
- APH402, Modern Instrumentation Analytical Technologies
- APH404, Modern Pharmaceutical Activity Screening
Awards and honours
- Shenzhen Longhua Chinese Dragon Plan Talent (level A), 2019
- Shenzhen Overseas High-Caliber Personnel (level C), 2019
- The Eurofed Lipid & Nordic Lipidforum Young Scientist Award, 2017

电话
+86 (0)51281883248
Email
Ken.Cheng@xjtlu.edu.cn
地址
P241(SIP Campus-Public Building)
Suzhou Dushu Lake Science and Education Innovation District
Suzhou Industrial Park
Suzhou
P.R.China
215123

Ken ChengPh.D.

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Courses taught

Awards and honours