Ongoing research projects

YEAR AWARDED	PROJECT NAME	PRINCIPAL INVESTIGATOR	FUNDING BODY
2023	Investigate the structures of different vaccines and antigens	Lanlan Han	NDA
2023	Detection of modification on nucleic acids with Oxford Nanopore technology	Rong Rong	Technical Service
2023	Development of RNA Modification Detection Method Based on Nanopore Sequencing	Zhen Wei	Cooperation
2023	Structure-based Development and Identification of Potential Inhibitors of SARS-CoV-2	Faez Khan	RDF
2023	Development of bioinformatics methods for MeRIP-Seq analysis	Zhen Wei	RDF
2022	Examination of G protein coupling profile of human GnRH receptor and its P128K mutant	Zhiliang Lu	RDF
2022	Energy harvesting and photovoltaic conversion properties of hybrid light-harvesting system	Xia Huang	RDF
2022	Developing an age-equivalent neuronal model for Alzheimer’s Disease	Chunmei Yue	RDF
2022	Suzhou Municipal Key Lab for Metabolic Syndrome Drug Research	Jia Meng	Suzhou Dushu Lake Science and Education Innovation District Management Committee
2021	Investigation of the genetic and environmental risk factors for diabetic retinopathy using the UK Biobank cohort	Weihua Meng	RDF
2021	Tumor-promoting roles of the chromatin-associated DEK oncogene in metastatic melanoma	Tatsuhiko Kadowaki	RDF
2021	Early diagnosis and clinical intervention of lung cancer	Jeong Hyeon Park	RDF
2020	Elucidating the chronic inflammatory response to different types of injuries which lead to post-traumatic osteoarthritis.	Pradeep Kumar Sacitharan	RDF
2020	Developing a software tool for epitranscriptome analysis from MeRIP-seq data	Jia Meng	REF
2020	Intrinsic bias and improved analysis approaches for methylated RNA immunoprecipitation sequencing	Jia Meng	KSF-Exploratory Research Programme
2020	Elucidating diet-induced epigenetic changes in arthritis	Pradeep Kumar Sacitharan	National Natural Science Foundation of China
2020	Cause of water pollution in Wujiang District. Project A of Water Science Project	Sekar Raju	Wujiang District Water Bureau / XJTLU UES URC
2019	A pipeline for the detection of antibiotic residue	Boris Tefsen	Others
2019	China Pangolin Research Center Cooperation Agreement	Siew Who Choo	Cooperation
2019	The functional interplay of cytoplasmic nucleoporins with SLP-76 and its regulatory roles in TCR signaling	Hebin Liu	KSF-Exploratory Research Programme
2019	Evaluation of novel microbial source tracking markers for identification of fecal contamination in inflow Rivers of Taihu Lake	Sekar Raju	KSF
2019	Novel microbial source tracking markers for identification of fecal contaminations in inflow rivers of Taihu Lake	Sekar Raju	PGRS
2019	To study a cytoplasmic form of transcription factor AP4 that can control cell morphology and migration	David Chiu	RDF
2019	Developing a software tool for epitranscriptome analysis from MeRIP-seq data	Jia Meng	REF
2019	Development of NanoBRET ligand binding assay of GnRH receptor for high throughput drug screening GnRH荧光配体及其NanoBRET受体结合高通量药物筛选技术的研发	Zhiliang Lu	KSF
2019	Searching multi-target drug hits using a new machine learning based QSAR approach 一种全新的基于机器学习算法的定量构效关系方法在多靶点药物设计中的应用	Xin Liu	KSF
2019	RNA 甲基化测序技术m6A-seq的系统性偏差以及数据分析方法优化	Jia Meng	KSF
2019	The role of RNA m6A methylation in host antiviral immunity	Rong Rong	KSF
2018	Decoding the genetic origins of the families of the imperial house of Ming Dynasty and ancient celebrities using DNA Technology	Siew Who Choo	Cooperation
2018	Construction of Bioinformatics Bioinformatics Plantform for Precision Medicine(Supplementary Notes on Project-Relevant Computer Hardware)	Jia Meng	Cooperation
2018	Construction of a Bioinformatics Platform for Precision Medicine (Supplemental Agreement)	Jia Meng	Cooperation
2018	Construction of a Bioinformatics Platform for Precision Medicine	Jia Meng	Technology Development (Commissioned Party)
2018	To study a cytoplasmic form of transcription factor AP4 that can control cell morphology and migration	David O’Connor	RDF
2018	Characterization of honey bee viral infection and replication using the honey bee and mite cell lines	Tatsuhiko Kadowaki	RDF
2018	Sarcoma family kinase signaling in migraine pathophysiology	Minyan Wang	RDF
2018	Intelligent Information Technology for Cancer Precision Diagnosis	Jia Meng	KSF-Technology Transfer Programme
2018	A pipeline for the detection of antibiotic residues	Boris Tefsen	KSF-Technology Transfer Programme
2018	Identification of drug targets involved in TRPA1 signaling for preventing classical migraine	Minyan Wang	KSF
2018	Dynamics of mRNA m6A methylome induced by hepatitis B virus X protein and its significance for the pathogenesis of hepatocellular carcinoma.	Rong Rong	RDF
2018	The role of long non-coding RNA and RNA m6A methylation in host antiviral immunity (Joint with SISM)	Rong Rong	PGRS
2018	Tumour-promoting roles of the chromatin-associated DEK oncogene in metastatic melanoma	Ferdinand Kappes	RDF
2017	Construction of a Bioinformatics Platform for Precision Medicine (Collaborate with Sano Medical Laboratories, Inc)	Jia Meng	Sano Medical Laboratories, Inc
2017	Stress-triggered neuroinflammation in migraine	Minyan Wang	Joint PhD with ISIS
2016	Bioinformatics approaches for RNA methylation-related high-throughput sequencing data and RNA methylome regulatory network reconstruction	Jia Meng	NSFC
2016	Reconstruct Gene Regulatory Network at Epitranscriptomic Layer with Non-parametric Bayesian Approach	Jia Meng	Jiangsu University Natural Science Research Programme
2016	Unravel the synergic regulation among different types of RNA modification	Jia Meng	RDF 2016
2016	Migraine mechanism: Cortical Spreading Depression induces CGRP expression involving ROS and TRPA1	Minyan Wang	RDF
2016	Biochemical and structural characterisation of microbial enzymes	David Ruiz Carrillo	RDF 2016
2016	Ligand-induced selective signalling of peptide GPCRs	Zhiliang Lu	PhD/PGR
2016	The discovery and identification of neoantigen from colorectal cancer for personalised immunotherapy	Zhiliang Lu	Joint PhD with ISIS
2014	Application of microbial source tracking to identify the fecal pollution in Taihu watershed across Tiaoxi River basin	Sekar Raju	Jiangsu Science and Technology Programme
2014	Methods for the differential analysis of RNA methylation sequencing data with small sample	Jia Meng	Jiangsu Science and Technology Programme
2014	Small sample based high-resolution differential analysis of RNA methylation sequencing data	Jia Meng	NSFC
2014	Molecular ecological study of trypanosomatid parasite infecting honey bee	Tatsuhiko Kadowaki	RDF 2014
2014	Unravel RNA methylome to identify key enzyme genes that directly lead to epitranscriptomic dys-regulation	Jia Meng	RDF 2014
2013	Microbial diversity-ecosystem function in canals across a gradient of urban intensification in Suzhou, China	Sekar Raju	Jiangsu University Natural Science Programme
2013	Molecular mechanisms of ligand-induced selective signalling at the gonadotropin-releasing hormone receptor	Zhiliang Lu	NSFC
2013	Characterisation of Simian Type D Retroviruses (SRV/D) from Monkeys in Chinese Breeding Colonies and Investigation of the Effects of SRV/D Infection on the autophagic pathway in infected cells	Rong Rong	PGRS
2013	Charaterisation of Simian Type D Retroviruses from Monkeys in Chinese Breeding Farms	Rong Rong	Jiangsu University Natural Science Research Programme
2013	Microbial diversity-ecosystem function in canals across a gradient of urban intensification in Suzhou, China	Sekar Raju	PGRS
2013	Investigation into pathogenesis of neurological diseases and identification of drug target and drug discovery	Minyan Wang	External charitable fund
2013	Identification of novel kisspeptin/GPR54-interacting proteins and their biological functions	Zhiliang Lu	PGRS
2012	Application of Microbial Source Tracking Techniques to Identify the Fecal Pollution into Taihu Lake, China	Sekar Raju	PGRS
2012	NR2A-containing receptor signalling in cortical spreading depression	Minyan Wang	PGRS
2012	Designing Tissue Inhibitors of Metalloproteinases (TIMPs) for Specific Inhibition against Membrane-Type1 Matrix Metalloproteinase (MT1-MMP) Involved in Cancer Metastasis	Meng Huee Lee	NSFC
2011	Molecular Assessment of Microbiological Quality of the Drinking Water in Suzhou region, China	Sekar Raju	RDF
2011	Identification of major pathogens and parasites causing honey bee diseases and development of their control methods (collaboration)	Tatsuhiko Kadowaki	Yamada Research Grant
2011	Global identification of protease substrates by terminus proteomics	David O’Connor	PGRS

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Ongoing research projects

Ongoing research projects