Ongoing research projects

Ongoing research projects
YEAR AWARDED PROJECT NAME PRINCIPAL INVESTIGATOR FUNDING BODY
2023 Investigate the structures of different vaccines and antigens Lanlan Han NDA
2023 Detection of modification on nucleic acids with Oxford Nanopore technology Rong Rong Technical Service
2023 Development of RNA Modification Detection Method Based on Nanopore Sequencing Zhen Wei Cooperation
2023 Structure-based Development and Identification of Potential Inhibitors of SARS-CoV-2 Faez Khan RDF
2023 Development of bioinformatics methods for MeRIP-Seq analysis Zhen Wei RDF
2022 Examination of G protein coupling profile of human GnRH receptor and its P128K mutant Zhiliang Lu RDF
2022 Energy harvesting and photovoltaic conversion properties of hybrid light-harvesting system Xia Huang RDF
2022 Developing an age-equivalent neuronal model for Alzheimer’s Disease Chunmei Yue RDF
2022 Suzhou Municipal Key Lab for Metabolic Syndrome Drug Research Jia Meng Suzhou Dushu Lake Science and Education Innovation District Management Committee
2021 Investigation of the genetic and environmental risk factors for diabetic retinopathy using the UK Biobank cohort Weihua Meng RDF
2021 Tumor-promoting roles of the chromatin-associated DEK oncogene in metastatic melanoma Tatsuhiko Kadowaki RDF
2021 Early diagnosis and clinical intervention of lung cancer Jeong Hyeon Park RDF
2020 Elucidating the chronic inflammatory response to different types of injuries which lead to post-traumatic osteoarthritis. Pradeep Kumar Sacitharan RDF
2020 Developing a software tool for epitranscriptome analysis from MeRIP-seq data Jia Meng REF
2020 Intrinsic bias and improved analysis approaches for methylated RNA immunoprecipitation sequencing Jia Meng KSF-Exploratory Research Programme
2020 Elucidating diet-induced epigenetic changes in arthritis Pradeep Kumar Sacitharan National Natural Science Foundation of China
2020 Cause of water pollution in Wujiang District. Project A of Water Science Project Sekar Raju Wujiang District Water Bureau / XJTLU UES URC
2019 A pipeline for the detection of antibiotic residue Boris Tefsen Others
2019 China Pangolin Research Center Cooperation Agreement Siew Who Choo Cooperation
2019 The functional interplay of cytoplasmic nucleoporins with SLP-76 and its regulatory roles in TCR signaling Hebin Liu KSF-Exploratory Research Programme
2019 Evaluation of novel microbial source tracking markers for identification of fecal contamination in inflow Rivers of Taihu Lake Sekar Raju KSF
2019 Novel microbial source tracking markers for identification of fecal contaminations in inflow rivers of Taihu Lake Sekar Raju PGRS
2019 To study a cytoplasmic form of transcription factor AP4 that can control cell morphology and migration David Chiu RDF
2019 Developing a software tool for epitranscriptome analysis from MeRIP-seq data Jia Meng REF
2019 Development of NanoBRET ligand binding assay of GnRH receptor for high throughput drug screening

GnRH荧光配体及其NanoBRET受体结合高通量药物筛选技术的研发

Zhiliang Lu KSF
2019 Searching multi-target drug hits using a new machine learning based QSAR approach

一种全新的基于机器学习算法的定量构效关系方法在多靶点药物设计中的应用

Xin Liu KSF
2019 RNA 甲基化测序技术m6A-seq的系统性偏差以及数据分析方法优化 Jia Meng KSF
2019 The role of RNA m6A methylation in host antiviral immunity Rong Rong KSF
2018 Decoding the genetic origins of the families of the imperial house of Ming Dynasty and ancient celebrities using DNA Technology Siew Who Choo Cooperation
2018 Construction of Bioinformatics Bioinformatics Plantform for Precision Medicine(Supplementary Notes on Project-Relevant Computer Hardware) Jia Meng Cooperation
2018 Construction of a Bioinformatics Platform for Precision Medicine (Supplemental Agreement) Jia Meng Cooperation
2018 Construction of a Bioinformatics Platform for Precision Medicine Jia Meng Technology Development (Commissioned Party)
2018 To study a cytoplasmic form of transcription factor AP4 that can control cell morphology and migration David O’Connor RDF
2018 Characterization of honey bee viral infection and replication using the honey bee and mite cell lines Tatsuhiko Kadowaki RDF
2018 Sarcoma family kinase signaling in migraine pathophysiology Minyan Wang RDF
2018 Intelligent Information Technology for Cancer Precision Diagnosis Jia Meng KSF-Technology Transfer Programme
2018 A pipeline for the detection of antibiotic residues Boris Tefsen KSF-Technology Transfer Programme
2018 Identification of drug targets involved in TRPA1 signaling for preventing classical migraine Minyan Wang KSF
2018 Dynamics of mRNA m6A methylome induced by hepatitis B virus X protein and its significance for the pathogenesis of hepatocellular carcinoma. Rong Rong RDF
2018 The role of long non-coding RNA and RNA m6A methylation in host antiviral immunity (Joint with SISM) Rong Rong PGRS
2018 Tumour-promoting roles of the chromatin-associated DEK oncogene in metastatic melanoma Ferdinand Kappes RDF
2017 Construction of a Bioinformatics Platform for Precision Medicine (Collaborate with Sano Medical Laboratories, Inc) Jia Meng Sano Medical Laboratories, Inc
2017 Stress-triggered neuroinflammation in migraine Minyan Wang Joint PhD with ISIS
2016 Bioinformatics approaches for RNA methylation-related high-throughput sequencing data and RNA methylome regulatory network reconstruction Jia Meng NSFC
2016 Reconstruct Gene Regulatory Network at Epitranscriptomic Layer with Non-parametric Bayesian Approach Jia Meng Jiangsu University Natural Science Research Programme
2016 Unravel the synergic regulation among different types of RNA modification Jia Meng RDF 2016
2016 Migraine mechanism: Cortical Spreading Depression induces CGRP expression involving ROS and TRPA1 Minyan Wang RDF
2016 Biochemical and structural characterisation of microbial enzymes David Ruiz Carrillo RDF 2016
2016 Ligand-induced selective signalling of peptide GPCRs Zhiliang Lu PhD/PGR
2016 The discovery and identification of neoantigen from colorectal cancer for personalised immunotherapy Zhiliang Lu Joint PhD with ISIS
2014 Application of microbial source tracking to identify the fecal pollution in Taihu watershed across Tiaoxi River basin Sekar Raju Jiangsu Science and Technology Programme
2014 Methods for the differential analysis of RNA methylation sequencing data with small sample Jia Meng Jiangsu Science and Technology Programme
2014 Small sample based high-resolution differential analysis of RNA methylation sequencing data Jia Meng NSFC
2014 Molecular ecological study of trypanosomatid parasite infecting honey bee Tatsuhiko Kadowaki RDF 2014
2014 Unravel RNA methylome to identify key enzyme genes that directly lead to epitranscriptomic dys-regulation Jia Meng RDF 2014
2013 Microbial diversity-ecosystem function in canals across a gradient of urban intensification in Suzhou, China Sekar Raju Jiangsu University Natural Science Programme
2013 Molecular mechanisms of ligand-induced selective signalling at the gonadotropin-releasing hormone receptor Zhiliang Lu NSFC
2013 Characterisation of Simian Type D Retroviruses (SRV/D) from Monkeys in Chinese Breeding Colonies and Investigation of the Effects of SRV/D Infection on the autophagic pathway in infected cells Rong Rong PGRS
2013 Charaterisation of Simian Type D Retroviruses from Monkeys in Chinese Breeding Farms Rong Rong Jiangsu University Natural Science Research Programme
2013 Microbial diversity-ecosystem function in canals across a gradient of urban intensification in Suzhou, China Sekar Raju PGRS
2013 Investigation into pathogenesis of neurological diseases and identification of

drug target and drug discovery

Minyan Wang External charitable fund
2013 Identification of novel kisspeptin/GPR54-interacting proteins and their biological functions Zhiliang Lu PGRS
2012 Application of Microbial Source Tracking Techniques to Identify the Fecal Pollution into Taihu Lake, China Sekar Raju PGRS
2012 NR2A-containing receptor signalling in cortical spreading depression Minyan Wang PGRS
2012 Designing Tissue Inhibitors of Metalloproteinases (TIMPs) for Specific Inhibition against Membrane-Type1 Matrix Metalloproteinase (MT1-MMP) Involved in Cancer Metastasis Meng Huee Lee NSFC
2011 Molecular Assessment of Microbiological Quality of the Drinking Water in Suzhou region, China Sekar Raju RDF
2011 Identification of major pathogens and parasites causing honey bee diseases and development of their control methods (collaboration) Tatsuhiko Kadowaki Yamada Research Grant
2011 Global identification of protease substrates by terminus proteomics David O’Connor PGRS