Dr. Ruiyao Wang's research area is on medicinal chemistry based on crystal engineering and coordination chemistry, which aims to develop new medicines underpinned by supramolecular chemistry, coordination and/or organometallic chemistry and crystal engineering, such as pharmaceutical polymorphism, pharmaceutical co-crystallization, as well as Pt(IV) complex-based prodrugs. Currently, Dr. Wang's research focuses on the development of 1) novel pharmaceutical cocrystals; 2) novel drug-drug pharmaceutical cocrystals for antitumor drugs; 3) targeted Pt(IV) complex-based prodrugs for antitumor applications; and 4) drug formulation.
Dr. Wang joined XJTLU in December, 2012 as an Associate Professor. Prior to XJTLU, Dr. Wang worked as the X-ray Lab manager and departmental X-ray crytsallographer at the Chemistry Department of Queen's University, Canada (2002-2012), post-doctorial fellow and research associate at the University of Arizona, US and Queen's University (1998-2001). He received his PhD from Peking University in 1997, and MS from Changchun Institute of Applied Chemistry, CAS. Dr. Wang has published over 150 research papers (https://scholar.google.com/citations?hl=zh-CN&user=dNtV9HMAAAAJ), and 3 book chapters. He also owns one US/Canada patent and one China patent.
Dr. Wang joined XJTLU in December, 2012 as an Associate Professor. Prior to XJTLU, Dr. Wang worked as the X-ray Lab manager and departmental X-ray crytsallographer at the Chemistry Department of Queen's University, Canada (2002-2012), post-doctorial fellow and research associate at the University of Arizona, US and Queen's University (1998-2001). He received his PhD from Peking University in 1997, and MS from Changchun Institute of Applied Chemistry, CAS. Dr. Wang has published over 150 research papers (https://scholar.google.com/citations?hl=zh-CN&user=dNtV9HMAAAAJ), and 3 book chapters. He also owns one US/Canada patent and one China patent.
- Ph.D. , Beijing University, - 1997
- MSc , Changchun Institute of Applied Chemistry, CAS, - 1990
- Senior Associate Professor, Chemistry Department, Xi'an Jiaotong-Liverpool University, Suzhou, China-2022 to present
- Associate Professor, Chemistry Department, Xi'an Jiaotong-Liverpool University, Suzhou, China-2012 to 2022
- X-ray Lab Manager/Departmental Crystallographer, Chemistry Department, Queen’s University, Canada - 2002 to 2012
- Research Associate, Chemistry Department, Queen’s University, Canada - 2000 to 2002
- Postdoctoral Fellow, Chemistry Department, University of Arizona, USA - 1998 to 2000
- Associate Professor, Chemistry Department, Xi’an Jiaotong-Liverpool University, China - 2012 to Present
- Teaching Assistant/Lecturer/Associate Head of the Department, Chemistry Department, College of Art and Sciences, Hebei Agricultural University, China - 1983 to 1998
- Dr. Ruiyao Wang's research area is on medicinal chemistry based on crystal engineering and coordination chemistry, which aims to develop new medicines underpinned by supramolecular chemistry, coordination and/or organometallic chemistry and crystal engineering, such as pharmaceutical polymorphism, pharmaceutical co-crystallization, as well as Pt(IV) complex-based prodrugs. Currently, Dr. Wang's research focuses on the development of 1) novel pharmaceutical cocrystals; 2) novel drug-drug pharmaceutical cocrystals for antitumor drugs; 3) targeted Pt(IV) complex-based prodrugs for antitumor applications; and 4) drug formulation.
- Wu, Xiaoyu; Che, Yu; Chen, Linjiang; Amigues, Eric Jean; Wang, Ruiyao; He, Jinghui; Dong, Huilong; Ding, Lifeng; Mapping the Porous and Chemical Structure-Function Relationships of Trace CH3I Capture by Metal-Organic Frameworks using Machine Learning. ACS Applied Materials & Interfaces (2022), 14(41), 47209–47221.
- Chen, Xiaocui; Zhou, Ruixue; Zhou, Hao; Yan, Tianhao; Ding, Lifeng; Zhang, Haifei; Wang, Ruiyao*; One-Pot Synthesis and Characterization of Three Chromotropic Supramolecular Isomeric Cu(II) Coordination Polymers as 1-D Zigzag or Helical Chains with Homochiral or Heterochiral Cu(II) Coordination Centres. Journal of Molecular Structure (2022), 1265, 133422.
- Hanifehpour, Younes; Mirtamizdoust, Babak; Dadashi, Jaber; Wang, Ruiyao; Rezaei, Mahboube; Abdolmaleki, Mehdi; Joo, Sang Woo; The Synthesis and Characterization of a Novel One-Dimensional Bismuth (III) Coordination Polymer as a Precursor for the Production of Bismuth (III) Oxide Nanorods. Crystals (2022), 12 (1), 113.
- Hanifehpour, Younes; Mirtamizdoust, Babak; Ahmadi, Hossein; Wang, Ruiyao; Joo, Sang Woo; Ultrasonic-assisted synthesis, characterizing the structure and DFT calculation of a new Pb(II)-chloride metal-ligand coordination polymer as a precursor for preparation of α-PbO nanoparticles. Journal of Molecular Structure (2021), 1224, 129031.
- Chao, Meng-Yao; Chen, Jing; Wu, Xiao-Yu; Wang, Rui-Yao; Wang, Pei-Pei; Ding, Lifeng; Young, David J.; Zhang, Wen-Hua; Unconventional Pyridyl Ligand Inclusion within a Flexible Metal-Organic Framework Bearing an N,N'-Diethylformamide (DEF)-Solvated Cd5 Cluster Secondary Building Unit. ChemPlusChem (2020), 85(3), 503-509.
- Yang, Siyuan; Chen, Linjiang; Holden, Daniel; Wang, Ruiyao; Cheng, Yuanyuan; Wells, Mona; Cooper, Andrew I.; Ding, Lifeng, Understanding the effect of host flexibility on the adsorption of CH4, CO2 and SF6 in porous organic cages. Zeitschrift fuer Kristallographie - Crystalline Materials (2019), 234(7-8), 547-555.
- Wang, Ruiyao; Aquino, Manuel A. S. 1,3-Bis(2,4,6-trimethylphenyl)imidazolium perchlorate. IUCrData (2019), 4(4), x190494.
- Abdou, Moaz M.; Matziari, Magdalini; O'Neill, Paul M.; Amigues, Eric; Zhou, Ruixue; Wang, Ruiyao; Ali, Basem F. Methyl 3-(4-hydroxyphenyl)propionate. IUCrData (2018), 3(11), x181662.
- Ge, Yuxin; Zhou, Hao; Ji, Yujin; Ding, Lifeng; Cheng, Yuanyuan; Wang, Ruiyao; Yang, Siyuan; Liu, Yufeng; Wu, Xiaoyu; Li, Youyong. Understanding Water Adsorption and the Impact on CO2 Capture in Chemically Stable Covalent Organic Frameworks. Journal of Physical Chemistry C (2018), 122(48), 27495-27506.
- Zhang, Ruizhong; Tong, Feng; Yang, Liuqing; Adsetts, Jonathan Ralph; Yan, Tianhao; Wang, Ruiyao; Ding, Zhifeng; Wang, Hong-Bo. Facile synthesis and efficient electrochemiluminescence of a readily accessible pyridopyrimidine. Chemical Communications (2018), 54(71), 9897-9900.
- Aquino, Manuel A. S.; Minaker, Samuel A.; Wang, Ruiyao. 1,3-Bis(2,6-diisopropylphenyl) imidazolium perchlorate. IUCrData (2018), 3, x180516.
- Hanifehpour, Younes; Mirtamizdoust, Babak; Wang, Ruiyao; Anbarteh, Saeed; Joo, Sang Woo, A Nano Nickel(II) Metal-Organic Coordination Compound for Nano Nickel (II) Oxide: Sonochemical Synthesis and Characterization. Journal of Inorganic and Organometallic Polymers and Materials (2017), 27(4), 1045-1052.
- Essoun, Ernest; Wang, Ruiyao; Aquino, Manuel A. S. Disassembly of diruthenium(II,III) tetraacetate with P-N donor ligands. Inorganica Chimica Acta (2017), 454, 97-106.
- Kandel, Ramjee; Huynh, Keith; Dalgliesh, Lauren; Wang, Ruiyao; Jessop, Philip G. Contrasting connectivity of amidine and phosphaamidine (1,3-P,N) Cu(I) complexes. Inorganica Chimica Acta (2016), 445, 117-123.
- Chen, Xiaocui; Han, Shumin; Wang, Ruiyao; Li, Yuan. Four supramolecular isomers of dichloridobis(1,10-phenanthroline)cobalt(II): synthesis, structure characterization and isomerization. Acta Crystallographica, Section C: Structural Chemistry (2016), 72(1), 6-13.
- Chen, Xiaocui; Wang, Yue; Han, Shumin; Wei, Yongju; Wang, Ruiyao, 4,4'-Bipyridine-1,1'-diium acetylenedicarboxylate: a new member of the (H2bipy)[Cu(ox)2] (bipy is 4,4'-bipyridine and ox is oxalate) family. Acta Crystallographica, Section C: Structural Chemistry (2015), 71(5), 357-362.
- Ang, M. Trisha C.; Phan, Lam; Alshamrani, Aliyah K.; Harjani, Jitendra R.; Wang, Ruiyao; Schatte, Gabriele; Mosey, Nicholas J.; Jessop, Philip G. Contrasting Reactivity of CS2 with Cyclic vs. Acyclic Amidines. European Journal of Organic Chemistry (2015), 2015(33), 7334-7343.
- Kong, Xianqi; Tang, Aaron; Wang, Ruiyao; Ye, Eric; Terskikh, Victor; Wu, Gang. Are the amide bonds in N-acyl imidazoles twisted? A combined solid-state 17O NMR, crystallographic, and computational study. Canadian Journal of Chemistry (2015), 93(4), 451-458.
- Fassler, Jurg; McCubbin, J. Adam; Roglans, Anna; Kimachi, Tetsutaro; Hollett, Joshua W.; Kunz, Roland W.; Tinkl, Michael; Zhang, Yousheng; Wang, Ruiyao; Campbell, Michael; et al. Highly Enantioselective (-)-Sparteine-Mediated Lateral Metalation-Functionalization of Remote Silyl Protected ortho-Ethyl N,N-Dialkyl Aryl O-Carbamates. Journal of Organic Chemistry (2015), 80(7), 3368-3386.
- Corkum, Elizabeth G.; Wang, Ruiyao; Aquino, Manuel A. S. Compromising the metal-metal bond in diruthenium(II,III) tetraacetate: Reaction of [Ru2(μ-O2CMe)4(MeOH)2]+ with phosphines to form 'Ru(μ-O2CMe)2(μ-OMe)2Ru' cores. Inorganica Chimica Acta (2015), 424, 202-209.
- Thomson, Michael P.; O'Rourke, Natasha F.; Wang, Ruiyao; Aquino, Manuel A. S. Crystal structure of tetrakis(μ-n-butyrato-κ2 O:O')bis[chloridorhenium(III)](Re-Re). Acta Crystallographica, Section E: Structure Reports Online (2014), 70(10), m349-m350.
- Keske, Eric C.; Moore, Brandon D.; Zenkina, Olena V.; Wang, Ruiyao; Schatte, Gabriele; Crudden, Cathleen M. Highly selective directed arylation reactions via back-to-back dehydrogenative C–H borylation/arylation reactions. Chemical Communications (Cambridge, United Kingdom) (2014), 50, 983-986.
- Dunlop, Kate; Wang, Ruiyao; Stanley Cameron, T.; Aquino, Manuel A. S. Coordination of weakly binding anions to [Ru2(μ-O2CCH3)4]+ in aqueous solution. Journal of Molecular Structure (2014), 1058, 122-129.
- O'Rourke, Natasha F.; Ronaldson, Michael; Stanley Cameron, T.; Wang, Ruiyao; Aquino, Manuel A. S. Equatorial π-stacking Interactions in Diruthenium (II,III) Tetracarboxylate Complexes Containing Extended π-systems. Journal of Molecular Structure (2013), 1052, 17-23.
- Groves, Brandon R.; Arbuckle, D. Ian; Essoun, Ernest; Lundrigan, Travis L.; Wang, Ruiyao; Aquino, Manuel A. S. , Chiral Induction at Octahedral Ru(II) via the Disassembly of Diruthenium(II,III) Tetracarboxylates Using a Variety of Chiral Diphosphine Ligands. Inorganic Chemistry (2013), 52(19), 11563-11572.
- Keske, Eric C.; Zenkina, Olena V.; Asadi, Ali; Sun, Hongsui; Praetorius, Jeremy M.; Allen, Daryl P.; Covelli, Danielle; Patrick, Brian O.; Wang, Ruiyao; Kennepohl, Pierre; et al. Dioxygen adducts of rhodium N-heterocyclic carbene complexes. Dalton Transactions (2013), 42(20), 7414-7423.
- Huynh, Keith; Napolitano, Krizia; Wang, Ruiyao; Jessop, Philip G.; Davis, Boyd R. Indirect hydrolysis of sodium borohydride: Isolation and crystallographic characterization of methanolysis and hydrolysis by-products. International Journal of Hydrogen Energy (2013), 38(14), 5775-5782.
- Zenkina, Olena V.; Keske, Eric C.; Kochhar, Gurpaul S.; Wang, Ruiyao; Crudden, Cathleen M. Heteroleptic rhodium NHC complexes with pyridine-derived ligands: synthetic accessibility and reactivity towards oxygen, Dalton Transactions (2013), 42(6), 2282-2293.
- Blight, Barry A.; Guillet-Nicolas, Remy; Kleitz, Freddy; Wang, Rui-Yao; Wang, Suning. Luminescent Triarylboron-Functionalized Zinc Carboxylate Metal-Organic Framework. Inorganic Chemistry (2013), 52(4), 1673-1675.
- Stevenson, Kristina A.; Melan, Caroline F. C.; Fleischel, Olivier; Wang, Ruiyao; Petitjean, Anne. Solid-State Self-Assembly of Triazolylpyridine-Based Helicates and Mesocate: Control of the Metal-Metal Distances. Crystal Growth & Design (2012), 12(11), 5169-5173.
- Chen, Xiaocui; Han, Shumin; Wang, Ruiyao, Crystal engineering through charge-assisted hydrogen bonds, multiple C-H···O bonds and π-π stacking: from (H2bipy)[Cu(ox)2] to (H2bipy)[NaH(ox)2] and (H2bipy)[H2(ox)2] (H2bipy = 4,4'-bipyridin-1,1'-dium; ox = oxalate) . CrystEngComm (2012), 14(20), 6400-6403.
- Cipot-Wechsler, Judy; Covelli, Danielle; Praetorius, Jeremy M.; Hearns, Nigel; Zenkina, Olena V.; Keske, Eric C.; Wang, Ruiyao; Kennepohl, Pierre; Crudden, Cathleen M. Synthesis and Characterization of Cationic Rhodium Peroxo Complexes. Organometallics (2012), 31(21), 7306-7315.
- Yan, Yi; Zhao, Weiwen; Bhagavathy, Ganga Viswanathan; Faurie, Alexandre; Wang, Ruiyao; Petitjean, Anne. Double-layered alcohol: controlling the macroscopic organization of small molecules through the self-assembly of their receptors. CrystEngComm (2012), 14(19), 6118-6120.
- Keske, Eric C.; Zenkina, Olena V.; Wang, Ruiyao; Crudden, Cathleen M. Synthesis and structure of palladium 1,2,3-triazol-5-ylidene mesoionic carbene PEPPSI complexes and their catalytic applications in the Mizoroki-Heck reaction. Organometallics (2012), 31(17), 6215-6221.
- Kong, Xianqi; ODell, Luke A.; Terskikh, Victor; Ye, Eric; Wang, Ruiyao; Wu, Gang, Variable-Temperature 17O NMR Studies Allow Quantitative Evaluation of Molecular Dynamics in Organic Solids. Journal of the American Chemical Society (2012), 134(35), 14609-14617.
- Artacho, Josep; Ascic, Erhad; Rantanen, Toni; Karlsson, Josefine; Wallentin, Carl-Johan; Wang, Ruiyao; Wendt, Ola F.; Harmata, Michael; Snieckus, Victor; Waernmark, Kenneth, Twisted Amide Analogues of Troeger's Base. Chemistry--A European Journal (2012), 18(4), 1038-1042.
- Zhao, Shu-Bin; Wang, Rui-Yao; Nguyen, Ha; Becker, Jennifer J.; Gagne, Michel R., Electrophilic fluorination of cationic Pt-aryl complexes. Chemical Communications (Cambridge, United Kingdom) (2012), 48(3), 443-445.
- Keske, Eric C.; Zenkina, Olena V.; Wang, Ruiyao; Crudden, Cathleen M., Synthesis and Structure of Silver and Rhodium 1,2,3-Triazol-5-ylidene Mesoionic Carbene Complexes. Organometallics (2012), 31(1), 456-461.
- Zenkina, Olena V.; Keske, Eric C.; Wang, Ruiyao; Crudden, Cathleen M., Double Single-Crystal-to-Single-Crystal Transformation and Small-Molecule Activation in Rhodium NHC Complexes. Angewandte Chemie, International Edition (2011), 50(35), 8100-8104.
- Capela, Marinha dF.; Mosey, Nicholas J.; Xing, Liyan; Wang, Ruiyao; Petitjean, Anne, Amine Exchange in Formamidines: An Experimental and Theoretical Study. Chemistry--A European Journal (2011), 17(16), 4598-4612.
- Wu, Ying-Lan; Wang, Jia-Fu; Kong, Xiang-Jian; Sheng, Chuan-Xiang; Wang, Rui-Yao; Peyghambarian, Nasser; Norwood, Robert A.; Zheng, Zhi-Ping, A dinuclear europium(III) complex with thenoyltrifluoroacetonato and 1-(2-pyridylazo)-2-naphtholato ligands and its optical properties. Inorganica Chimica Acta (2011), 370(1), 346-352.
- Luo, Qun; Wu, Dayong; Liu, Shixiong; Tang, Daihua; Huang, Yong; Liu, Xinhou; Wang, Fuyi; Wang, Ruiyao; Wu, Gang, The formation of thymidine-based T-tetramers with remarkable structural and metal ion size effects. Organic & Biomolecular Chemistry (2011), 9(4), 1030-1033.
- Reid, Derek J.; Cull, John E. W.; Chisholm, Kimberley D. S.; Langlois, Alexandre; Lin, Po-Heng; Long, Jerome; Lebel, Olivier; Korobkov, Ilia; Wang, Ruiyao; Wuest, James D.; et al, Synthesis, structure and magnetism of homodinuclear complexes of Co, Ni and Cu supported by a novel bitriazine scaffold. Dalton Transactions (2011), 40(18), 5009-5017.
- Beach, Michael T.; Walker, Jesse M.; Wang, Ruiyao; Spivak, Gregory J., Ruthenium piano-stool complexes containing mono- or bidentate pyrrolidinylalkylphosphines and their reactions with small molecules. Journal of Organometallic Chemistry (2011), 696(20), 3198-3205.
- Zhao, Weiwen; Wang, Ruiyao; Mosey, Nicholas J.; Petitjean, Anne, Alkoxyamine-derived Formamidines: Configurational Control and Molecular Folding. Organic Letters (2011), 13(19), 5160-5163.
- Zhao, Weiwen; Wang, Ruiyao; Petitjean, Anne, Z-Formamidoximes in molecular folding and macrocycles. Organic & Biomolecular Chemistry (2011), 9(22), 7647-7651.
- Amarne, Hazem; Baik, Chul; Wang, Rui-Yao; Wang, Suning. Photoisomerization of 1-Phenyl-2-(pyridin-2-yl)indole BMes2: The Dark Isomer. Organometallics (2011), 30(4), 665-668.
- Zenkina, Olena V.; Keske, Eric C.; Wang, Ruiyao; Crudden, Cathleen M., Dimeric Rhodium-Ethylene NHC Complexes As Reactive Intermediates for the Preparation of Tetra-heteroleptic NHC Complexes, Organometallics (2011), 30(23), 6423-6432.
- Wang, Ruiyao, David, A. Atwood, John, Wiley & Sons, Limited 2012, 'Chapter 25. Carboxylate' in (eds) Encyclopedia of Inorganic and Bioinorganic Chemistry, The Rare Earth Elements: Fundamentals and Applications, John Wiley and Sons, Inc, pp.
- Wang, Ruiyao & Chunhui, Huang 2010, 'Chapter 3. Rare Earth Complexes with Carboxylic Acids, Polyaminopolycarboxylic Acids, and Amino Acids.' in (eds) Coordination Chemistry of Rare Earth: From Fundamentals to Applications, VHS-Wiley, pp.
- Wang, Ruiyao & Chunhui, Huang 2010, 'Chapter 6. Coordination Chemistry of Rare Earth Alkoxides, Aryloxides, and Hydroxides.' in (eds) Coordination Chemistry of Rare Earth: From Fundamentals to Applications, VHS-Wiley, pp.
- 1995 Guanghua Scholarship for PhD Students, Peking Uiniversity, China
Contact information
Telephone:+86 (0)51288161437
Address:P237(SIP Campus-Public Building)
Suzhou Dushu Lake Science and Education Innovation District
Suzhou Industrial Park
Suzhou
P.R.China
215123
Suzhou Dushu Lake Science and Education Innovation District
Suzhou Industrial Park
Suzhou
P.R.China
215123