School of Science 
Register DETAILS
■ Time: 12:00-13:00
■ Date: Friday, January 5, 2024
■ Venue: SB220(Onsite)
■ Alternative online Tencent Meeting Link: https://meeting.tencent.com/dm/36O9rx9rlHX0
Meeting ID: 797-245-440
■ Title: Sensing endogenous and exogenous metabolites for tumor progression
■ Presenter: Prof Xu Qian, Nanjing Medical University
■ Event Host: Dr. Weiwei Dai, Department of Biological Sciences, XJTLU
ABSTRACT
OUTLINE:
1. Metabolic reprogramming in cancers
2. Sensing endogenous metabolite, fumarate, for tumor progression
3. Sensing exogenous temozolomide-derived AICA for AMPK activation
Key words:
metabolic reprogramming, post-translational modification, metabolite sensing
SPEAKER
Dr Qian is a Professor at Nanjing Medical University. He is now serving the Chair of Department of Nutrition and Food Hygiene and the Director of Core Facility of School of Public Health. Dr. Qian received his PhD degree by investigating the roles of microRNAs in tumor progression in Nanjing Medical University. During his post-doc training, Dr. Qian focused on the regulation mechanisms underlying glucose metabolism on promoting gliomas. After joining Nanjing Medical University in 2018, Dr. Qian was selected for Young Scholar of National Major Talent Project. His research interest focuses on the mechanisms underlying sensing nutrient metabolites and trace metal elements for tumorigenesis. As corresponding author, he has published research papers in prestigious scientific journals including Science Translational Medicine (2023, accepted in principle), Molecular Cell (2019a, 2019b, 2022a, 2022b), Cancer Research (2023, cover story), and Cell Reports (2023). Dr. Qian is serving a committee member of Society of Special Nutrition, Chinese Nutrition Society, and a standing committee member of Jiangsu Nutrition Society, China.
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