Research Output

Research Output

Publications

  • Song, J., Zhang, Y., Frieler, R. A., Andren, A., Wood, S., Tyrrell, D. J., Sajjakulnukit, P., Deng, J. C., Lyssiotis, C. A., Mortensen, R. M., Salmon, M., & Goldstein, D. R. (2024). Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice. Journal of Clinical Investigation, 134(3), Article e173034.
  • Tong, X., Luo, D., Leung, M. H. Y., Lee, J. Y. Y., Shen, Z., Jiang, W., Mason, C. E., & Lee, P. K. H. (2024). Diverse and specialized metabolic capabilities of microbes in oligotrophic built environments. Microbiome, 12(1), Article 198.
  • Lyu J., Gu, Z., Zhang Y., Vu, H. Lechauve C., Cai F., Cao H., Keith J., Brancaleoni V., Granata F., Motta I., Cappellini M. , Huang L., DeBerardinis R., Weiss M., Ni M., Xu J. (2024). A glutamine metabolic switch supports erythropoiesis. Science. 2024 Nov 15;386(6723):eadh9215.
  • Dai, W., Tian, R., Yu, L., Bian, S., Chen, Y., Yin, B., Luan, Y., Chen, S., Fan, Z., Yan, R., Pan, X., Hou, Y., Li, R., Chen, J., & Shu, M. (2024). Overcoming therapeutic resistance in oncolytic herpes virotherapy by targeting IGF2BP3-induced NETosis in malignant glioma. Nature Communications, 15(1), Article 131.
  • Song, J. (2024). Endosomal protein DENND10/FAM45A integrates extracellular vesicle release with cancer cell migration. BMC Biology, 22(1).
  • Sloboda, S., Ge, X., Jiang, D., Su, L., Wiens, G., Beveridge, C., Duchaud, E., McBride, M. J., Rochat, T., & Zhu, Y. (Accepted/In press). Methylation of foreign DNA overcomes the restriction barrier of Flavobacterium psychrophilum and allows efficient genetic manipulation. Applied and Environmental Microbiology.

Projects

NSFC Grant

  1. NSFC General Program #32470825: The mechanism of ammonia accumulation promotes liver cancer progression via calcium channel-mTORC2-SREBP1-lipogenesis dependent manner. 1/01/25 → 31/12/28, Weiwei Dai (PI), 500,000 RMB.
  2. NSFC General Program #82470860: The mechanism of amino acid metabolic reprogramming mediated by glucose metabolic enzyme PCK2 promotes diabetic myocardial fibrosis. 1/01/25 → 31/12/28, Yu Feng (PI), 480,000 RMB.
  3. NSFC Young Scientists Fund: Study on the mechanism of DMGV-induced functional impairment of pancreatic β-cells and early progression of type 2 diabetes. 1/01/25 → 31/12/27, Ken Cheng (PI), 300,000 RMB.