Xi'an Jiaotong-Liverpool University

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Dr. Jie Zhang is the Associate Professor of XJTLU Wisdom Lake Academy of Pharmacy. She obtained her PhD with Professor Xuetao Pei from Academy of Military Medical Science, investigating stem cell differentiation. She then worked as the Associate Director of R&D Center at 3SBio Group. Her research aimed around biopharmaceutical screening and gene reconstruction.

Dr. Jie Zhang became an entrepreneur afterward and founded NEST Biotech, UP-Pharma, and Planter Stem Cell Biotech, which covered the application of Biotech into cell culture consumables, GLP-complied large molecule pharmacokinetics outsourcing, and TCM cultivation. Since 2009, her research interests have been aiming at Plant Stem Cell-originated TCM Cultivation. She has developed a TCM large-scale production platform based on plant stem cell biopharmaceutical techniques.

Dr. Zhang's research mainly focuses on the following directions:

• Mechanism of skin/mucosa inflammation
• Multi-omics study of inflammation
• TCM metabonomics

Qualifications
- Ph.D., Stem Cell Differentiation, Academy of Military Medical Science, Beijing, China, 2003
- M.S., Molecular Biology, 4th Military Medical University, Xi'an, China, 1998
Experience
- 2016 – present--- Suzhou Planter Stem Cell Biotech Co., Ltd. Entrepreneur, Chairman
- 2009 - 2013 --- United-Power Pharma Tech Co., Ltd. (UP-Pharma), Entrepreneur, Vice President, QUA Director
- 2007 - 2009 --- WuxiNest biotech Co., Ltd. Entrepreneur, CEO
- 2003 - 2006 --- 3SBio Pharmaceutical Inc. (3SBio in NASDAQ, 01530.HK), Associate Director of R&D Institute, Shenyang, China
- 1998 - 2000 --- Assistant research fellow, Laser Medical Department of Institute of Radiation Medicine, Academy of Military Medical Science, Beijing.
Research interests
- Mechanism of skin/mucosa inflammation
- Multi-omics study of inflammation
- TCM metabonomics
- Scale-up cultivation of Triditional Chinese Dedicine (TCM)
Articles
- Patent 1: ZHANG JIE. A large-scale cell culture process for dendrobium officinale Kimura et Migo. Publication No. : CN201610305801A. Publication Date: 2017.11.17
- Patent 2: ZHANG JIE. A dendrobium embryoid large-scale culture process. Publication No. : CN107347635A. Publication Date: 2017.11.17
- Patent 3: ZHANG JIE; WANG XINYI; WU HONGSHENG. Culture medium for increasing content of dendrobium officinale immature-stem extract and preparation method thereof. Publication No. : CN109548641A. Publication Date: 2018.12.28
- Patent 4: ZHANG JIE; WANG XINYI; WU HONGSHENG. Humic acid culture medium for improving growth speed of dendrobium candidum young stems and preparation method thereof. Publication No. : CN109548626A. Publication Date: 2019.04.02
- Patent 5: ZHANG JIE; WANG XINYI; WU HONGSHENG. Polysaccharide liquid culture medium and preparation method thereof. Publication No. : CN109548624A. Publication Date: 2019.04.02
- Patent 6: ZHANG JIE; WANG XINYI; WU HONGSHENG. Method for detecting polysaccharides in dendrobium officinale shoots. Publication No. : CN109738427A. Publication Date: 2019.05.10
- Patent 7: ZHANG JIE; WANG XINYI; WU HONGSHENG. Filtering method suitable for dendrobium officinale tender shoot stock solution. Publication No. : CN109793691A. Publication Date: 2019.05.24
- Patent 8: ZHANG JIE; WANG XINYI; WU HONGSHENG. Filtering method suitable for dendrobium officinale dry bud stock solution. Publication No. : CN109793692A. Publication Date: 2019.05.24
- Patent 9: ZHANG JIE; WANG XINYI; WU HONGSHENG. Liquid culture medium suitable for tender stems of dendrobium officinale and preparation method of liquid culture medium. Publication No. : CN109662030A. Publication Date: 2019.04.23
- Patent 10: ZHANG JIE; WANG XINYI; WU HONGSHENG. Liquid culture medium suitable for tender stems of Dendrobium officinale and preparation method thereof. Publication No. : CN109548625A. Publication Date: 2019.04.02
- Patent 11: ZHANG JIE; WANG XINYI; WU HONGSHENG. Liquid culture medium suitable for immature stems of dendrobium officinale and preparation method thereof. Publication No. : CN109601382A. Publication Date: 2019.04.12
- Patent 12: LOU JING;GENG JIANLING;ZHANG JIE. Hemopoietin analogue. Publication No. : CN103073631A. Publication Date: 2007.07.02
- Patent 13: LOU JING;GENG JIANLING;ZHANG JIE. New erythrocyte-stimulating factor analogues. Publication No. : CN101337988B. Publication Date: 2013.01.09
- Patent 14: JIE ZHANG;LU JUN;SHIYANG SHEN. 96-hole cell culture plate without edge effect. Publication No. : CN101348767B. Publication Date: 2009.01.21
- 1. Zhang Jie, Xu Fengguo. Study on liquid culture system of dendrobium candidum with high yield and high biological activity. Jiangsu Agricultural Science, 2019, 47(6): 43-47
- 2. Zhao Lianxu, Zhang Jie, Meng Ling, et al. Modification of the brain-derived neurotrophic factor gene: a portal to transform mesenchymal stem cells into advantageous engineering cells for neuroregeneration and neuroprotection. Exp Neurol. 2004; 190(2):396-406
- 3. Zhao LX, Zhang J, Xu XH, Pei XT. Stem cell and gene therapy: theory, technology and the prospectof application. StemCell& Cellular Therapy 2003; 1(2):10-17
- 4. ZHANG Jie, SHAN Qing, MA Ping, JIANG Yanming, CHEN Peng, WEN Jingxia, ZHOU You, QIAN Huanwen & PEI Xuetao，Differentiation potential of bone marrow mesenchymal stem cells into retina in normal and laser-injured rat eye，SciChinaC Life Sci. 2004 Jun; 47(3):241-250.
- 5. Zhang Jie, Shan Qing, Ma Ping et al. Bone marrow mesenchymalstem cells can differentiate into retina in normal and laser-injured rat eye. Sci China C Life Sci (Chinese). 2004; 34(1): 41~48
- 6. Zhang Jie, Shan Qing, Ma Ping et al. Observation of bone marrow mesenchymal stem cells aftersubretinally transplanted into laser-injured rat retina. Zhonghua Yi Xue Za Zhi. 2003 Nov; 83(22):1993-8.
- 7. Zhang Jie, Shan Qing, Ma Ping et al. Bone Marrow Mesenchymal Stem Cells Can Differentiate Into Retina-like Structure in situ. Clin J.Ophthalmol. 23（2）：82-85
- 8. Zhang Jie, Shan Qing, Ren Hua et al. The image analysis of laser-burn corneal lesions after interleukin-1receptorantagonisttreatment. Clin.J. Laser Med. Surg. 10(4): 230-233, 2001
- 9. Zhang Jie, Shan Qing, Wu Xiaobing et al. Evaluation of Adeno-Associated Virus-Mediated Gene TransferInto The Rabbit Retina.Journalof Tumor markerOncology 16(4): 287, 2001
- 10. Jie Zhang Qing Shan Huanwen Qian et al. Stable Expression of Human bcl-2 Antisense RNA Promotes Apoptosis of Human Gastric Cancer Cell Line SGC7901. Journal of Tumor marker Oncology 16(4): 365, 2001
- 11. Zhang Jie, Qian Huanwen, Shan Qing et al. Therapeutic effect of recombinant human basic fibroblast growth factor on laser induced retina injuries in rhesus monkeys. Clin. J. Laser Med. Surg. 8(2): 92-95, 1999
- 12. Zhang Jie, Peng Weidan, Wang Duoning et al. The construction and evaluation of expression efficiency of an inducible mammalian _expression vector. J. Fourth Mil. Med. Univ. 20(4): 280-283, 1999
- 13. Zhang Jie, Peng Weidan, Hui Hongxiang et al. Inducible _expression of bcl-2 antisense RNA promtes apoptosis of human gastric cancer cell line. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (ACTA Biochimica et Bipphysica Scinica), 31 (3): 279-283, 1999 Pubmed ID:12136178 (In Chinese)
- 14. Zhang Jie, Peng weidan, Hui Hongxiang et al. the construction of a inducible mammalian _expression vectorwithmultyclone sites.J. FourthMil. Med.Univ. 19(2): 229-230, 1998
Proceedings
- Bone Marrow Mesenchymal Stem Cells Can Differentiate Into Retina-like Structure in vivo, 4th International Symposium of Ophthalmology, Shantou, China.June 2002
- Bone Marrow Mesenchymal Stem Cells Can Differentiate Into Retina-like Structure in vivo, The VIII Congress of Chinese Clinic and FundamentalResearch and Therapy, Kunming, China. May 2002
- Study On Adeno-Associated Virus-Mediated Gene Transfer Into The Rabbit Retina, The VII Congress of Chinese Ophthalmological Society Shanghai, China. Sept. 2000
Chapters, cases, readings and supplements
- 1. Wang Yuming and Gu Changhai, New Progress in Infection, People's Medical Publishing House, 2001
- 2. Han Demin and Wang Ningli, New Advances in Ophthalmology, People's Medical Publishing House, 2002
- 3. Pei Xuetao, Stem Cell Biology, Science Press, 2003
- 4. Da Wanming, Pei Xuetao, Ed., Modern Hematology, , People's Military Medical Press, 2003
Conference presentations
- 2000, The VII Congress of Chinese Ophthalmological Society Shanghai, China. Sept. 2000 / Study On Adeno-Associated Virus-Mediated Gene Transfer Into The Rabbit Retina
- 2002, The VIII Congress of Chinese Clinic and FundamentalResearch and Therapy, Kunming, China. May 2002 / Bone Marrow Mesenchymal Stem Cells Can Differentiate Into Retina-like Structure in vivo
- 2002, 4th International Symposium of Ophthalmology, Shantou, China.June 2002 / Bone Marrow Mesenchymal Stem Cells Can Differentiate Into Retina-like Structure in vivo.
- 2006, European ForumI of the Life Sciences PartneringChina& Europe / The Chinese Life Science Market: Opportunities and Threads, Munich, Germany
- 2010, PSWC& AAPS Annual Meeting & Exposition, New Orleans / Poster: The process of GLP-complied hardwear management, November, 2010
Grants
- 2017, The leading talents of Suzhou Industrial Park / The leading talents of Suzhou Industrial Park
- 2017, Suzhou Municipal GUSU leading talents / Modernization cultivation of Traditional Chinese Medicine (TCM)
- 2003, AMMS Youth Fund, Bone Marrow Mesenchymal Stem Cells Can Differentiate Into Retina-like Structure in vivo.
Teaching activities
- Experience of teaching and training 3 PG and one PhD to obtain their degree at Academy of Military Medical Science
- Experience of teaching undergraduate the experimental classes at 4th Military Medical University
Professional memberships
- Chinese Society of Biological Engineering
Awards and honours
- Suzhou Women Pace-Setter awarded, 2021
- The Best Entrepreneurs Awarded, Win The Future (TV Program), 2018
- Suzhou Industrial Park Pioneer Entrepreneur awarded, 2017
- Suzhou City Pioneer Entrepreneur awarded, 2017
- Represented China to attend Biopharma Bilateral Talks with EU, 2005
- Awarded First prize for Scientific and Technological Progress, 1998

电话
+86 (0)51288973082
电子邮件
Jie.Zhang03@xjtlu.edu.cn
地址
P250(SIP Campus-Public Building)
Suzhou Dushu Lake Science and Education Innovation District
Suzhou Industrial Park
Suzhou
P.R.China
215123

Jie ZhangPH.D.

Profile

Qualifications

Experience

Research interests

Articles

Proceedings

Chapters, cases, readings and supplements

Conference presentations

Grants

Teaching activities

Professional memberships

Awards and honours