ProfileChunmei received her Bachelor degree in biological science from Qufu Normal University, Shandong. She got her Master degree in genetics at Zhejiang University, where she developed the interest in molecular and cell biology and started to work on a wide variety of projects relevant to these two directions from then on. In 2003, she completed her Ph.D program in oncology under the guidance of Prof. ShihHxin Lu at Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing.
She then moved to the USA for her postdoctoral training at the National Institute of Neurological Disorders and Stroke (NINDS) of National Institutes of Health (NIH), where she started her research in neuroscience under the supervision of Dr. Harold Gainer. In 2009, she returned to China and served as an associate professor at Shanghai Institute of Biochemistry and Cell Biology. During that time, she established her research program in Alzheimer’s disease (AD), which mainly focused on modeling AD as well as exploring novel therapies for AD. She has generated patient iPSC-based cellular models and non-human primate models for AD, reproducing the neuropathological hallmarks of AD in live AD neurons in vitro and in the non-human primates in vivo. She has tested the potential of human neural stem cells as donor cells for treating AD in both AD mouse and aged monkeys, assessing the possible application of stem cell-based replacement therapy for AD.
She joined the Department of Biological Sciences at Xi’an Jiaotong-Liverpool University in 2020.