Professor Lei Fu received his B.Sc. and M. Sc. degrees in Chemistry from Fudan University, Shanghai, China, and his Ph.D. degree in Chemistry from Stanford University under the direction of Dr. James P. Collman. He joined Pharmacyclics Inc. (then acquired by AbbVie), California in 1998 as a scientist and then a group leader. He led the drug discovery & development, process research on anti-cancer and anti-cardiovascular diseases. He has been a Summer visiting scholar in the Department of Chemistry, Stanford University since 2009, and a scientific consultant to several pharmaceutical companies.
Dr. Lei Fu has been a Professor of Medicinal Chemistry at Shanghai Jiao Tong University since March of 2006. The research in his group interfaces chemistry and medicine. His principal interests are 1) drug discovery and development; 2) process research on drug API and related substances; 3) traditional Chinese medicines as botanical cosmeceuticals; 4) medical devices as targeted drug delivery systems and 5) human hibernation studies using biomimetic models of cytochrome c oxidase. Dr. Fu teaches undergraduate and graduate courses, including Principles of Medicinal Chemistry, Comprehensive Pharmacy, Presenting Science, Chemistry and Pharmacology for layman etc.
Professor Fu jointed Xi’an Jiaotong – Liverpool University Academy of Pharmacy as an Associate Dean for Learning and Teaching in early 2021. He is responsible for strategic establishment of the Academy and its curriculums.
Dr. Fu is an adjunct Professor at Roosevelt University and Santa Clara University in the US, also an Editor of Bioorganic Chemistry (Elsevier) and Pharmaceutical Fronts (Thieme), respectively.
Dr. Fu has over 80 peer-reviewed publications mainly in drug discovery. Several of them were published in Science, PNAS, Chemical Reviews, Angewandte Chemie International Edition, Journal of American Chemical Society, Accounts of Chemical Research, Journal of Medicinal Chemistry, Journal of Organic Chemistry and European Journal of Medicinal Chemistry. He holds more than 20 US and China Patents.
Dr. Fu invented two cosmeceutical products containing traditional Chinese medicines (TCMs) and licensed to German companies, Henkel and Beiersdorf, respectively.
Dr. Fu initiated a collaborative research project with Ethiopia Addis Ababa University, Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa, supported by the World Bank and State government), on the development of Africa local medicinal herbal and establishment of Africa herbal pharmacopeia.
Topic: When Oxygen Goes Mad: A Wild Tale of Life and Chaos
Abstract: Oxygen is our best friend—until it isn’t. We breathe it, our cells use it to make energy, and life as we know it wouldn’t exist without it. But here’s the twist: oxygen has a dark side! When mitochondria process oxygen to power our bodies, they accidentally create tiny troublemakers called free radicals. These unstable molecules bounce around, damaging cells like tiny wrecking balls. Luckily, our body has an army of antioxidants to keep them in check—until the balance tips.
When oxygen “goes mad,” oxidative stress can fuel diseases like cancer and Alzheimer’s and even speed up aging. Scientists are on a mission to outsmart rogue oxygen, using AI to design new medicines and therapies. Oxygen therapy can be life-saving or dangerous, depending on the dose. So, the big question is: can we tame oxygen’s power without getting burned? The answer could change the future of medicine!
20 March
Speaker: Professor Lei Fu
Professor Lei Fu received his B.Sc. and M. Sc. degrees in Chemistry from Fudan University, Shanghai, China, and his Ph.D. degree in Chemistry from Stanford University under the direction of Dr. James P. Collman. He joined Pharmacyclics Inc. (then acquired by AbbVie), California in 1998 as a scientist and then a group leader. He led the drug discovery & development, process research on anti-cancer and anti-cardiovascular diseases. He has been a Summer visiting scholar in the Department of Chemistry, Stanford University since 2009, and a scientific consultant to several pharmaceutical companies.
Dr. Lei Fu has been a Professor of Medicinal Chemistry at Shanghai Jiao Tong University since March of 2006. The research in his group interfaces chemistry and medicine. His principal interests are 1) drug discovery and development; 2) process research on drug API and related substances; 3) traditional Chinese medicines as botanical cosmeceuticals; 4) medical devices as targeted drug delivery systems and 5) human hibernation studies using biomimetic models of cytochrome c oxidase. Dr. Fu teaches undergraduate and graduate courses, including Principles of Medicinal Chemistry, Comprehensive Pharmacy, Presenting Science, Chemistry and Pharmacology for layman etc.
Professor Fu jointed Xi’an Jiaotong – Liverpool University Academy of Pharmacy as an Associate Dean for Learning and Teaching in early 2021. He is responsible for strategic establishment of the Academy and its curriculums.
Dr. Fu is an adjunct Professor at Roosevelt University and Santa Clara University in the US, also an Editor of Bioorganic Chemistry (Elsevier) and Pharmaceutical Fronts (Thieme), respectively.
Dr. Fu has over 80 peer-reviewed publications mainly in drug discovery. Several of them were published in Science, PNAS, Chemical Reviews, Angewandte Chemie International Edition, Journal of American Chemical Society, Accounts of Chemical Research, Journal of Medicinal Chemistry, Journal of Organic Chemistry and European Journal of Medicinal Chemistry. He holds more than 20 US and China Patents.
Dr. Fu invented two cosmeceutical products containing traditional Chinese medicines (TCMs) and licensed to German companies, Henkel and Beiersdorf, respectively.
Dr. Fu initiated a collaborative research project with Ethiopia Addis Ababa University, Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa, supported by the World Bank and State government), on the development of Africa local medicinal herbal and establishment of Africa herbal pharmacopeia.
Topic: When Oxygen Goes Mad: A Wild Tale of Life and Chaos
Abstract: Oxygen is our best friend—until it isn’t. We breathe it, our cells use it to make energy, and life as we know it wouldn’t exist without it. But here’s the twist: oxygen has a dark side! When mitochondria process oxygen to power our bodies, they accidentally create tiny troublemakers called free radicals. These unstable molecules bounce around, damaging cells like tiny wrecking balls. Luckily, our body has an army of antioxidants to keep them in check—until the balance tips.
When oxygen “goes mad,” oxidative stress can fuel diseases like cancer and Alzheimer’s and even speed up aging. Scientists are on a mission to outsmart rogue oxygen, using AI to design new medicines and therapies. Oxygen therapy can be life-saving or dangerous, depending on the dose. So, the big question is: can we tame oxygen’s power without getting burned? The answer could change the future of medicine!